Depression is a heavy burden that affects the mind, body, and spirit. It can leave a person feeling hopeless, drained, and unable to find joy in life. While professional care and support are vital, prayer remains one of the strongest sources of comfort and healing. A prayer for someone depressed lifts them into God’s presence, asking for strength, peace, and renewed hope.
God’s Care for the Brokenhearted
The Bible reminds us that God is close to those who are hurting. Psalm 34:18 says, “The Lord is nigh unto them that are of a broken heart; and saveth such as be of a contrite spirit.” Depression may make someone feel isolated, but scripture assures us that God sees, understands, and draws near to the hurting.
Jesus Himself invited the weary in Matthew 11:28: “Come unto me, all ye that labour and are heavy laden, and I will give you rest.” This rest includes emotional and spiritual relief that only He can provide.
A Prayer for Someone Depressed
Heavenly Father, I lift up to You the one who is struggling under the weight of depression. Lord, You see their pain, their sleepless nights, and the heaviness they carry each day. I ask that You bring them comfort in their darkest moments and remind them that they are not alone. Fill their heart with Your peace that passes all understanding. Restore joy where sadness has taken root. Give them strength to take each day step by step, and surround them with people who will love and encourage them. May they know that their life has value, and that You have plans to give them hope and a future. In Jesus’ name, Amen.
Additional Prayers for Specific Needs
Prayer for Peace of Mind
Lord, calm the anxious thoughts and silence the lies that weigh heavily on their heart. Replace fear with faith and despair with hope.
Prayer for Strength
God, give them strength to face each day and courage to seek help when they need it. Remind them that weakness is not failure, for Your strength is made perfect in weakness.
Prayer for Healing
Heavenly Father, touch their mind and body with Your healing hand. Renew their spirit and restore balance to every area of their life.
Prayer for Hope
Lord, let the light of Your promises break through the darkness of depression. May they remember that weeping endures for a night, but joy comes in the morning (Psalm 30:5).
Encouraging Scriptures for the Depressed
- Psalm 42:11 – “Why art thou cast down, O my soul? and why art thou disquieted within me? hope thou in God: for I shall yet praise him.”
- Isaiah 41:10 – “Fear thou not; for I am with thee: be not dismayed; for I am thy God: I will strengthen thee.”
- Philippians 4:13 – “I can do all things through Christ which strengtheneth me.”
- Romans 15:13 – “Now the God of hope fill you with all joy and peace in believing.”
These verses offer encouragement, reminding believers that depression does not define them and that God’s promises remain true even in difficult seasons.
Supporting Someone in Prayer
Praying for someone who is depressed is powerful, but practical support matters as well. Listening without judgment, encouraging professional help, and showing consistent care can be just as healing as words of prayer. Depression can make a person feel unseen, so prayer combined with action shows the love of Christ in tangible ways.
Final Thoughts
Depression is real and painful, but God’s Word brings assurance that healing and hope are possible. A prayer for someone depressed calls on God’s compassion, power, and presence to lift them from despair into peace.
When prayer is joined with scripture, encouragement, and community support, it becomes a lifeline for those battling inner struggles. Even in the darkest valleys, God remains the Good Shepherd who walks with His people and restores their souls.